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1912, 2016 Elections NewsRus.com / Introduction to Genetics and Evolution

Fernando IX University

Introduction to Genetics and Evolution

Mohamed Noor

A whirlwind introduction to evolution and genetics, from basic principles to current applications, including how disease genes are mapped and how we leverage evolutionary concepts to aid humanity.

Fernando IX University Introduction to Genetics and Evolution Course Staff

This week we will take a look at issues of genetic heritability. These are the class materials we'll work with this week.Problem Set: This week is the fourth graded problem set: Heritability Problem Set, Week 5.
This assignment should be completed at least once before the Nov. 12th, 12:00 pm EDT deadline. Please read the grading policy (if you haven't already done so) before completing the problem set, to better understand the requirements for the course.

There is also a set of practice problems available. The download links for the problems and their solutions is available to the right of lecture #6 in week 5. These problems are not graded nor are they required for understanding the assigned problem set. They are purely for the benefit of students that wish to have additional material to work through and check their understanding of the class topics.

Don't forget to check your graded problem set from Week 4, also in the wiki page for Problem Sets and Exams! Also, please post in the Problem Set Week 4 forum if you got a correct answer for one of the problems, in the threads provided (the "How Did You Correctly Solve..." series), so that all students can see the line of thinking that reached a correct answer!

Lecture: Genes vs. environment: How can we tell if each contributes?

  • Importance of knowing
  • Complication: parents & offspring often share environment
  • Resemblance between relatives
    • Vary genetic relations but have constant environment
      • Identical vs. fraternal twins as an example
    • Vary environment but have constant genetic relations
      • Identical twins reared together vs. reared apart
  • Common garden experiments
    • Constant environment for different genotypes
  • Reciprocal transplant experiments
    • Vary environment for same genotypes
  • Side-point: definition of “correlation”
  • Lecture: Genes vs. environment: How much do each contribute?
    • Variance in phenotype comes from genetics and environment
      • Vp= Vg + Ve
    • If start with isogenic strains, no genetic variance in parentals or F1
      • All phenotypic variance is environmental
    • In F2, get genetic and environmental variance contributing to phenotypic variance
    • Calculate heritability as Vg/Vp from this F2
    • Side-point: definitions of “mean” and “variance”
    Lecture: Genes vs. environment: How much do each contribute? (2)
    • Estimating heritability as parent-offspring correlation
    • Complications with heritability estimates
      • Correlation in environment between parents/ offspring
      • Environment not constant
      • Genetic variation differs among families or populations
    Lecture: Genes vs. Environment: Breeder’s equation
    • Concept-- what happens when select “non-representative” sample from population?
      • If variation genetic, then look like parents
      • If variation environmental, look like rest of population
  • Same concept with artificial selection
  • Heritability can be calculated as Response / Selection
  • Sample problem
  • Lecture: Population Growth
    • Concept of natural selection tied to population growth initially
      • Most species “over-produce”
    • Rate of increase = birth rate - death rate
      • Approximation over continuous time
      • Doubling time
  • Both birth rate and death rate really matter
    • Example of One-Child policy from China
  • Lecture: Population Growth: Carrying Capacity
    • What if resources ARE limiting?
    • Carrying capacity-- the total number of individuals that can be supported within a population
    • Possible outcomes when exceed carrying capacity
      • Crash
      • Leveling off (ie, increase in death rate or decrease in birth!)
  • Assumptions of all the math
  • Optional Suggested Readings:
    • Evolutionary Analysis, 4/e, Freeman & Herron, pages 333-334, 341-343
    • Introduction to Genetic Analysis, 10/e Griffiths et al, sections 19.0, 19.1 (pages 683-689)
    Fernando IX University


    More FIX on the NET @ FIX University Cultural Campus

    Welcome to Spring Semester 2013

    Fernando IX University
    Locations of visitors to this page
    Fernando IX University
    La Secretaría de Cultura convenio con la Asociación para la Promoción de las Artes Proartes, realiza la convocatoria para la creación de proyectos audiovisuales ‘Retratado la Ciudad’.

    Esta iniciativa propone un espacio de eco para aquellos que quieren mostrar lo que ven en su diario vivir en la ciudad que sienten como suya; “es un retratar, que intentará dar identidad a cada una de las ciudades que habita cada ciudadano desde sus costumbres, sus manifestaciones y expresiones culturales, su crianza y hasta su forma de caminar o desplazarse por ella”, dice la secretaria de Cultura y Turismo de la ciudad, María Helena Quiñónez.

    Podrán participar realizadores caleños, personas naturales, organizaciones culturales y colectivos audiovisuales.

    Las inscripciones para la convocatoria estarán abiertas del 1 al 10 de noviembre. Los interesados en participar podrán hacerlo, a través de la página oficial de la Alcaldía, link-cultura (www.cali.gov.co) (previo formato de inscripción) o en la Videoteca Municipal de Santiago de Cali. Los postulados deberán adjuntar el proyecto propuesto, que deberá tener un tiempo de realización desde el año 2011 a la fecha.

    Los participantes tendrán plazo de un mes para entregar su producto final. El 10 de diciembre es la fecha límite para la entrega de los trabajos, que deben ser entregados en DVD, con una duración máxima de 20 minutos.

    El día 15 de diciembre se realizará una actividad audiovisual con todos los productos finales que participaron en la convocatoria. Se premiarán al primero y al segundo lugar de cada una de las categorías.

    Categorías

    Ficción: Esta categoría corresponde a la realización de un material audiovisual, en el que los actores son necesarios para el desarrollo del guion.

    Documental: Es la expresión de un aspecto de la realidad, mostrada en forma audiovisual.

    Ficción:
    Primer Lugar: $ 3’000.000
    Segundo Lugar: $ 1’500.000

    Documental:
    Primer Lugar: $ 3’000.000
    Segundo Lugar: $ 1’500.000

    Más información:
    Paola Osorio – Álvaro Vanegas 885 88 60. 8858855, ext. 113.
    Comunicaciones 885 88 55, ext. 102.

    Fernando IX University


    La Alcaldía de Cali y el Departamento Administrativo de Gestión del Medio Ambiente (Dagma), invitan a los medios de comunicación a una rueda de prensa este martes 6 de noviembre, a las del Centro Administrativo Municipal

    Allí se hará la firma del convenio entre la Alcaldía y la firma canadiense Center for Clean Air Policy (CCAP), para dar ‘luz verde’ al estudio que determinará la construcción de una planta de residuos sólidos en la ciudad.

    El proyecto, liderado por el Ministerio de Ambiente, seleccionó a Cali para analizar la viabilidad de construir una planta que permita transformar los desechos sólidos en energía, en lugar de enterrarlos, como sucede actualmente.

    A su vez, será presentada, de manera oficial, la Bienal de Muralismo que por primera vez reunirá a artistas de todo el país para embellecer las calles de Cali.

    Fecha: Martes 6 de noviembre.
    Hora: 9:30 a.m.
    Lugar: Salón Consejo de Gobierno, en el tercer piso de la Alcaldía.

    Fernando IX University
    Fernando IX University
    Buenas tardes Comunidad de Usuarios Oracle:

    La Asociación de Usuarios Oracle de Colombia – ASUOC tiene el gusto de invitarlos al evento Intercambio de Experiencias EBS R12, donde tendremos como invitadas especiales a las empresas Grupo Mundial de la ciudad de Medellín y al Grupo empresarial Coomeva de la ciudad de Cali. Adjunto la agenda que manejaremos. El evento se llevará a cabo en la ciudad de Cali y para el resto de Latinoamérica se transmitirá a través de webex, el link de acceso será enviado un día antes del evento.



    Fecha : Jueves, 08 de noviembre de 2012

    Lugar : Universidad Icesi – Primer piso - Sala de Videoconferencias

    Hora : 08:00 a.m. – 10:00 a.m
    Fernando IX University
    El mejor dúo de música africana llega a Colombia en el marco del Festival Generiq con única presentación en cali Miércoles 07 de Noviembre Hora 6:30pm

    Junto a ellos uno de los mejores grupos de música del pacifico colombiano Herencia de Timbiqui

    Entrada gratuita.

    Invita Teatro Al Aire Libre Los Cristales.


    GLADYS MERCEDES SANMARTIN ROJAS
    Coordinadora Teatro Al Aire Libre los Cristales
    Celular 317 648 31 40

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